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Best Stuffed Italian Meatloaf – Easy Cheesy Family Comfort Dinner

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This Stuffed Italian Meatloaf is a savory blend of ground beef, Italian seasoning, and melted cheese, all wrapped up in a flavorful loaf. The stuffed center adds a juicy twist to the classic meatloaf. Perfect for a hearty family dinner!

  • Total Time: 1 hour 10 minutes
  • Yield: 6–8 servings

Ingredients

Scale
  • Meatloaf:
  • 1 1/2 lbs ground beef
  • 1/2 lb ground Italian sausage
  • 1 small onion, finely chopped
  • 2 cloves garlic, minced
  • 1 cup bread crumbs
  • 2 large eggs
  • 1/2 cup Parmesan cheese, grated
  • 2 tbsp Italian seasoning
  • 1 tbsp parsley, chopped
  • 1/2 cup milk
  • Salt and pepper to taste
  • Filling:
  • 1 cup mozzarella cheese, shredded
  • 1 cup spinach, chopped (optional)
  • 1/4 cup marinara sauce
  • Topping:
  • 1/2 cup marinara sauce
  • 1/4 cup Parmesan cheese, grated

Instructions

  1. Preheat oven to 375°F.
  2. In a large bowl, combine ground beef, Italian sausage, onion, garlic, bread crumbs, eggs, Parmesan cheese, Italian seasoning, and parsley. Add milk, salt, and pepper, then mix until fully combined.
  3. Form the mixture into a rectangular loaf on a baking sheet.
  4. Create a well in the center and fill with mozzarella, spinach (if using), and marinara sauce.
  5. Fold the meat around the filling, sealing edges to form a loaf.
  6. Spread marinara sauce on top and sprinkle with Parmesan cheese.
  7. Bake for 45–55 minutes, until internal temperature reaches 160°F.
  8. Let rest for 10 minutes before slicing and serving.

Notes

  • Add mushrooms, bell peppers, or olives for variation.
  • Store leftovers in an airtight container for up to 3 days.
  • Freeze wrapped meatloaf for up to 3 months and thaw before reheating.
  • Author: lily
  • Prep Time: 15 minutes
  • Cook Time: 55 minutes
  • Category: Dinner
  • Method: Baking
  • Cuisine: Italian