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Spaghetti with Cheesy Alfredo Three-Cheese Parmesan and Cajun Chicken

Spaghetti with Cheesy Alfredo Three-Cheese Parmesan and Cajun Chicken

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This Spaghetti with Cheesy Alfredo Three-Cheese Parmesan and Cajun Chicken is a rich, creamy pasta dish loaded with tender Cajun-seasoned chicken and a decadent blend of Parmesan, mozzarella, and cheddar cheeses. Perfect for an indulgent weeknight dinner ready in just 30 minutes.

  • Total Time: 30 minutes
  • Yield: 4 servings

Ingredients

Scale
  • 12 oz spaghetti pasta
  • 1 lb boneless, skinless chicken breast, cut into bite-sized pieces
  • 2 tablespoons olive oil
  • 1 1/2 teaspoons Cajun seasoning
  • 3 tablespoons unsalted butter
  • 4 cloves garlic, minced
  • 1 1/2 cups heavy cream
  • 1/2 cup freshly grated Parmesan cheese
  • 1/2 cup shredded mozzarella cheese
  • 1/2 cup shredded sharp cheddar cheese
  • 1 teaspoon Italian seasoning
  • Salt and freshly ground black pepper, to taste
  • 1/4 teaspoon crushed red pepper flakes (optional)
  • 1/4 cup chopped fresh parsley, for garnish

Instructions

  1. Cook spaghetti in a large pot of salted boiling water according to package instructions until al dente. Drain and set aside.
  2. Toss chicken with Cajun seasoning. Heat olive oil in a large skillet over medium-high heat. Cook chicken for 5–7 minutes until cooked through and golden brown. Remove from skillet and set aside.
  3. In the same skillet, melt butter over medium heat. Add garlic and sauté for 30 seconds until fragrant.
  4. Pour in heavy cream and bring to a gentle simmer. Stir in Parmesan, mozzarella, and cheddar cheeses until melted and smooth.
  5. Add Italian seasoning and crushed red pepper flakes if using. Season with salt and pepper to taste.
  6. Return chicken to the skillet and stir to coat in the cheese sauce. Add cooked spaghetti and toss to combine thoroughly.
  7. Garnish with chopped parsley before serving.

Notes

  • For extra smoky flavor, use smoked cheddar or smoked paprika along with the Cajun seasoning.
  • Adjust Cajun seasoning to your spice preference.
  • Reheat leftovers gently with a splash of milk or cream to restore creaminess.
  • Author: lily
  • Prep Time: 10 minutes
  • Cook Time: 20 minutes
  • Category: Dinner
  • Method: Stovetop
  • Cuisine: American